I have begun using an OTC antidepressant called sam- e, short for s-adenosyl – methionine. I have 200 mg pills. Few weeks of 1/4 pill per day, few weeks of 1/3 pill per day, now I’m up to 1/2 pill per day. First thing in the morning on an empty stomach. Doesn’t make it go away but takes some of the edge off. I have also been using betaine aka trimethylglycine or TMG. I worked slowly up to 1 tsp per day early in the morning. I also need my docosahexaenoic acid (DHA) and EPA , and these you can get either from fish oil or algae oil or just eating a lot of canned sardines– I eat almost one can almost every day. I am also considering trying low dose OTC lithium orotate or lithium aspartate. I have been eating a lot of potatoes because they are supposed to be high in lithium.